Zeeshan Fazal's Bioinformatics Blog

What is Bioinformatics?

June 07, 2025

An introduction to the exciting interdisciplinary field that combines biology, computer science, and statistics.

How to QC CRAM/BAM Files with Samtools

June 08, 2025

Tips for checking the completeness and usability of your CRAM/BAM files before variant calling or analysis.

Essential BCFtools Commands for VCF Analysis

June 10, 2025

Use bcftools to filter, view, query, and extract key statistics from your VCF files effectively.

Parsing VEP-Annotated VCFs into TSV Format

June 11, 2025

Learn how to use R and vcfR/ensemblVEP libraries to extract both VEP annotations and VCF info in a clean TSV format for downstream analysis.

NGS & File Formats: A Quick Guide for Bioinformatics Beginners!

June 13, 2025

A beginner-friendly overview of common NGS file formats (FASTQ, BAM/CRAM, VCF) and their roles in a typical sequencing workflow.